Gadolinium-based contrast enhanced MR angiogram technique is widely used to assess carotico-vertebral system, renal artery, lower limb run-off for peripheral vascular disease, and left atrium and pulmonary vein for pre-ablation anatomical mapping. In recent years, there has been rising concern of a rare gadolinum-related disease named nephrogenic systemic fibrosis (NSF). To avoid this potential complication, FDA of USA and EMA of European Community recommend that only macrocyclic MRI contrast should be used in these examinations.
Our centre follows the FDA and EMA of EC guidelines.